When conception comes with a huge price: a case report of giant uterine leiomyoma co-existing with pregnancy
DOI:
https://doi.org/10.4314/wnjms.v8i1.12Keywords:
Intra-abdominal mass, Laparotomy, Pregnancy, Uterine leiomyoma, Caesarean SectionAbstract
Introduction: The management of huge intra-abdominal mass in pregnancy, a rare condition, involves careful evaluation and occasional surgical intervention. Low and middle-income countries are specifically faced with late and often-time, life-threatening presentations of this condition. The managing team should be equipped with the relevant clinical skills to care for this category of patients despite the limited resources at their disposal.
Case report: We report a case of a 38-year-old primigravida who presented with a history of progressive abdominal swelling and weight loss of 6 years, as well as severe respiratory distress of 4 months. She had a background history of primary infertility for 14 years and menstrual irregularity of 6 years. The patient had a positive serum pregnancy test and radiological findings in keeping with a giant intra-abdominal mass and a viable pregnancy. An assessment of huge intra-abdominal mass co-existing with pregnancy was made. She eventually had laparotomy with removal of the mass and preservation of the pregnancy after initial resuscitation. The histology of the mass revealed a uterine leiomyoma. The Pregnancy progressed to term and was delivered of a live male neonate via a caesarean section.
Conclusion: Huge uterine fibroid in pregnancy poses a great challenge because of the associated risks and complications during surgical intervention. However, early detection and prompt decision-making processes reduce or prevent morbidity and mortality from the condition.
References
Suwandinata FS, Gruessner SE, Omwandho CO, Tinneberg HR. Pregnancy-preserving myomectomy: Preliminary report on a new surgical technique. Eur J Contracept Reprod Health Care. 2008; 13(3):323-326. DOI: https://doi.org/10.1080/13625180802075281
Jhalta P, Negi SG, Sharma V. Successful myomectomy in early pregnancy for a large asymptomatic uterine myoma: A case report. Pan Afr Med J. 2016; 24(1):228. DOI: https://doi.org/10.11604/pamj.2016.24.228.9890
Aziken ME, Osaikhuwuomwan JA, Osemwenkha AP, Olokor OE, Iribhoghe I, Uwagboe CU. Pregnancies complicated by uterine fibroids. A case series on myomectomy in early pregnancy. Trop J Obstet Gyaecol. 2017; 34(2):160-4. DOI:https://doi.org/10.4103/TJOG.TJOG_2417
Kim MS, Lee GH, Choi MC, Park H, Jung SG, Kim KA. Respiratory arrest caused by a large uterine myoma. S Afr J Obstet Gyaecol. 2016; 22(2):67-68. DOI:10.7196/SAJOG.2016.v22i2.1094
Ahmed N, Khan TA, Saleem MM, Bhatti O, Zahid MA. Huge Abdominal mass in a young unmarried lady-A social and psychotherapeutic challenge. Cureus. 2021; 13(4):e14672. DOI: https://doi.org/10.7759%2Fcureus.14672
Erfani H, Chiang S, Dickinson S, Chi DS, Kim SH. When it’s not ovarian cancer: A case report of a massive leiomyoma with hydropic change. Gynecol Oncol Rep. 2024; 53:101415. DOI: https://doi.org/10.1016/j.gore.2024.101415
Malvasi A, Tinelli A, Cavalloti C, Morroni M, Tsin DA, Nezhat C et al. Distribution of Substance P (SP) and vasoactive intestinal peptide (VIP) in pseudocapsules of uterine fibroids. Peptides. 2011; 32(2):327-32. DOI: https://doi.org/10.1016/j.peptides.2010.10.034
Prapas Y, Zikopoulos A, Petousis S, Xiromeritis P, Tinelli A, Ravanos K, et al. Single layer suturing in intracapsular myomectomy of intramural myoma is sufficient for a normal wound healing. Eur J Obstet Gynecol Reprod Biol. 2020; 248:204-210. DOI: https://doi.org/10.1016/j.ejogrb.2020.03.042
Ohashi N, Imai H, Tobira T, Ishii H, Baba H. Anaesthetic management in a patient with giant growing teratoma syndrome. A case report. J Med Case Rep. 2014; 8:32. DOI: 10.1186/1752-1947-8-32.
Ochsenbein-Kolble N, Krahenmann F, Husler M, Meuli M, Moehrlen U, Mazzone L, et al. Tocolysis for in-utero surgery: Atosiban performs distinctly better than Magnesium Sulfate. Fetal Diagn Ther. 2018; 44(1):59-64. DOI: https://doi.org/10.1159/000478261

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