Non-secretory Multiple Myeloma in a 37-year old pregnant woman in Owo: A Case Report

Authors

  • Boma Paul-Odo Federal Medical Centre, Owo, Ondo State
  • Matthew Tomisin Adaja Federal Medical Centre Owo https://orcid.org/0000-0003-3553-3651
  • Julius Oluloro Federal Medical Centre, Owo, Ondo State
  • Oluwatoyin Adetan Federal Medical Centre, Owo, Ondo State

Keywords:

multiple myeloma, non-secretory, protein electrophoresis

Abstract

Introduction: This is a report of non-secretory multiple myeloma in a young woman.

Case report: A 39-year old pregnant woman presented with chest pain, weight loss, generalized joint pain, body weakness, bilateral knee join swelling and fractures of the left humerus and distal femur. Investigations revealed leukocytosis, elevated plasma alkaline phosphatase, negative serum protein electrophoresis and Bence Jones protein, anaemia and elevated erythrocyte sedimentation rate. Skull X-ray showed moth-eaten appearance in keeping with myelomatosis. She had intrauterine foetal death; and was managed subsequently as a case of non-secretory multiple myeloma with chemotherapy and had a tremendous improvement.

Conclusion: This case illustrates the occurrence of patients with multiple myeloma who do not secrete immunoglobulins in our environment.

Author Biographies

Boma Paul-Odo, Federal Medical Centre, Owo, Ondo State

Consultant Haematologist

Department of Haematology and Blood Transfusion

Matthew Tomisin Adaja, Federal Medical Centre Owo

Consultant Chemical Pathologist

Department of Chemical Pathology

Julius Oluloro, Federal Medical Centre, Owo, Ondo State

Senior Medical Officer,

Department of Haematology

Oluwatoyin Adetan, Federal Medical Centre, Owo, Ondo State

Consultant Orthopaedic Surgeon

Department of Orthopaedics

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Published

30-06-2024

How to Cite

Paul-Odo, B., Adaja, M. T., Oluloro, J., & Adetan, O. (2024). Non-secretory Multiple Myeloma in a 37-year old pregnant woman in Owo: A Case Report. Western Nigeria Journal of Medical Sciences, 7(1), 87–93. Retrieved from https://wnjms.com.ng/journal/index.php/wnjms/article/view/220